Metabolic signatures of youth exposure to per- and polyfluoroalkyl substances

BACKGROUND AND AIM: Human exposure to per- and polyfluoroalkyl substances (PFAS), including perfluorooctane sulfonate (PFOS), perfluorohexane sulfonic acid (PFHxS), and perfluorononanoic acid (PFNA) is ubiquitous and has been associated with increased risk of metabolic disorders. Exposure during periods of development, including childhood, may exacerbate these effects. The purpose of this study was to identify metabolic pathways associated with...