Exposure to perfluoroalkyl substances (PFAS) and liver injury: a systematic review and meta-analysis

BACKGROUND AND AIM: Experimental evidence indicates that exposure to pollutants is associated with liver damage and “toxicant-associated fatty liver disease” (TAFLD). Perfluoroalkyl substances (PFAS) are synthetic chemicals widely used in industry and consumer products that persist in the environment and bioaccumulate in food webs and human tissues. Our objective was to systematically review the literature evaluating PFAS exposure and evidence...