Methods for intratumoral microdialysis probe targeting and validation in murine brain tumor models
Abstract
Microdialysis is a well validated sampling technique that can be used for pharmacokinetic studies of oncological drugs targeting the central nervous system. This technique has also been applied to evaluate tumor metabolism and identify pharmacodynamic biomarkers of drug activity. Despite the potential utility of microdialysis for therapeutic discovery, variability in tumor size and location hamper routine use of microdialysis as a preclinical...
Paper Details
Title
Methods for intratumoral microdialysis probe targeting and validation in murine brain tumor models
Published Date
Nov 1, 2021
Volume
363
Pages
109321 - 109321
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