Production of bioactive glass/chitosan scaffolds by freeze-gelation for optimized vancomycin delivery: Effectiveness of glass presence on controlling the drug release kinetics

The major objective of this work was the creation of vancomycin loaded composite scaffolds designed for bone treatment from inexpensive and biocompatible materials such as chitosan. Bioactive glass was chosen as filler due to its outstanding bioactivity and ability for bone regeneration. The scaffolds were prepared using the freeze-gelation method, which was efficient and cost-effective. They included different glass contents (0, 25, and 50 wt...