Orientational changes of white matter fibers in Alzheimer's disease and amnestic mild cognitive impairment

Volume: 42, Issue: 16, Pages: 5397 - 5408
Published: Aug 19, 2021
Abstract
White matter abnormalities represent early neuropathological events in neurodegenerative diseases such as Alzheimer's disease (AD), investigating these white matter alterations would likely provide valuable insights into pathological changes over the course of AD. Using a novel mathematical framework called “Director Field Analysis” (DFA), we investigated the geometric microstructural properties (i.e., splay, bend, twist, and total distortion)...
Paper Details
Title
Orientational changes of white matter fibers in Alzheimer's disease and amnestic mild cognitive impairment
Published Date
Aug 19, 2021
Volume
42
Issue
16
Pages
5397 - 5408
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