Bispecific Antibodies in Multiple Myeloma: Present and Future
Abstract
Despite many recent advances in therapy, there is still no plateau in overall survival curves in multiple myeloma. Bispecific antibodies are a novel immunotherapeutic approach designed to bind antigens on malignant plasma cells and cytotoxic immune effector cells. Early-phase clinical trials targeting B-cell maturation antigen (BCMA), GPRC5D, and FcRH5 have demonstrated a favorable safety profile, with mainly low-grade cytokine release syndrome,...
Paper Details
Title
Bispecific Antibodies in Multiple Myeloma: Present and Future
Published Date
Aug 17, 2021
Journal
Volume
2
Issue
5
Pages
423 - 433
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History