No Association of filaggrin copy number variation and atopic dermatitis risk in White and Black Americans
Abstract
Atopic dermatitis (AD) is a chronic, inflammatory skin condition with a multifactorial pathophysiology. The filaggrin gene (FLG) has particularly been implicated given loss of function (LoF) mutations in this gene lead to skin barrier dysfunction and such mutations can increase a patient's likelihood of developing AD. FLG has intragenic copy number variation (CNV), which impacts the total amount of filaggrin produced. Previous research reported...
Paper Details
Title
No Association of filaggrin copy number variation and atopic dermatitis risk in White and Black Americans
Published Date
Aug 21, 2021
Journal
Volume
31
Issue
2
Pages
233 - 236
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