Pancreatic/peripancreatic neurogenic tumor; little known masses not to be missed.

Published on Aug 18, 2021in Pancreatology3.996
· DOI :10.1016/J.PAN.2021.08.005
Dong Wan Seo70
Estimated H-index: 70
(UOU: University of Ulsan)
Abstract null null Background null Retroperitoneal neurogenic tumors are extremely rare pathological entities; therefore, few clinical features and natural courses, especially originating from the pancreatic/peripancreatic regions, have been reported. This study aimed to investigate the clinicopathological features of pancreatic and peripancreatic neurogenic tumors and assess the diagnostic value of computed tomography (CT) and endoscopic ultrasound-guided fine needle biopsy (EUS-FNB). null null null Methods null Between 2006 and 2018, patients who were diagnosed with neurogenic tumors were included. In total, 90 histologically confirmed cases of neurogenic tumors located in the pancreatic/peripancreatic regions were selected for analysis. null null null Results null The mean age was 49.2 ± 13.1 years. There were no differences in sex distribution of the tumors. Schwannomas (44.4%) and paragangliomas (41.1%) were the most common neurogenic tumors. The sensitivity of CT was 62.2% in 90 cases. EUS-FNB was performed in 30 cases and the sensitivity of it was 83.3%. The diagnosis of neurogenic tumors with EUS-FNB or CT was not significantly associated with tumor location and size. Surgical resection was performed in 78 cases. Of the 12 patients who did not undergo surgery, 10 cases were followed-up without any increase in tumor size. null null null Conclusions null Through the present study, we verified radiological, pathological, and clinical aspects of the pancreatic/peripancreatic neurogenic tumors which little known before, therefore, this study can serve as the basis for research to present an optimal diagnosis and treatment of neurogenic tumors. In addition, EUS-FNB is useful in the diagnosis of pancreatic/peripancreatic neurogenic tumors with relatively high sensitivity and can help establish therapeutic plans before the surgery.
📖 Papers frequently viewed together
#1Alberto LarghiH-Index: 32
#2Erminia ManfrinH-Index: 26
Last. Adele FornelliH-Index: 18
view all 13 authors...
Abstract Background and Aims The recent development of microforceps for endoscopic ultrasound (EUS) through-the-needle biopsy (TTNB) of the wall of pancreatic cystic lesions (PCLs) allows to acquire histological specimens, which pathologists never handled and evaluated before. We aimed to estimate the interobserver agreement among pathologists in evaluating such samples. Methods TTNB slides from 40 PCLs with worrisome features were retrieved and independently evaluated for specimen adequacy, pre...
#1Mihai Rimbas (UMFCD: Carol Davila University of Medicine and Pharmacy)H-Index: 9
Last. Alberto Larghi (FUI: Foundation University, Islamabad)H-Index: 4
view all 6 authors...
#1Yuntong Ma (SYSU: Sun Yat-sen University)H-Index: 1
#2Bingqi Shen (SYSU: Sun Yat-sen University)H-Index: 2
Last. Shi Ting Feng (SYSU: Sun Yat-sen University)H-Index: 15
view all 9 authors...
Pancreatic schwannoma is a rare tumor. Preoperative diagnosis of pancreatic schwannoma is challenging due to its tendency to mimic other lesions of the pancreas. We describe a case of pancreatic schwannoma and present a review of the cases currently reported in the English literature to identify characteristics of pancreatic schwannoma on imaging. A 53-year-old male presented with a history of intermittent periumbilical abdominal pain and lower back pain for 1 week. Based on ultrasound (US) and ...
#1Stefano Francesco Crinò (University of Verona)H-Index: 16
#2Laura Bernardoni (University of Verona)H-Index: 13
Last. Armando Gabbrielli (University of Verona)H-Index: 29
view all 5 authors...
#2Amogh SrivastavaH-Index: 3
#3Edina E. PaalH-Index: 2
Last. Koenraad J. MorteleH-Index: 65
view all 5 authors...
The pathologic and radiologic characteristics of various benign nonepithelial neoplasms arising in the pancreas are reviewed, with emphasis on specific features that allow differentiation from primary pancreatic adenocarcinoma.
#1Jorge Delgado (Children's Hospital of Philadelphia)H-Index: 11
#2Diego Jaramillo (UPenn: University of Pennsylvania)H-Index: 60
Last. Sudha A. Anupindi (UPenn: University of Pennsylvania)H-Index: 21
view all 5 authors...
Aim To describe magnetic resonance imaging (MRI) findings of plexiform neurofibromas (PNF) involving the liver and pancreas in paediatric patients with neurofibromatosis type 1 (NF1). Materials and methods A retrospective search of the hospital database was undertaken to find cases of PNF in the porta hepatis, hilar neurofibroma, and hepatic neurofibroma over a 12 year period. The images were analysed and a review of the charts was undertaken. Results Five paediatric patients were identified wit...
#1Prabhakar Rajiah (Cleveland Clinic)H-Index: 26
#2Rakesh Sinha (Warwick Hospital)H-Index: 12
Last. Orpheus Kolokythas (UW: University of Washington)H-Index: 20
view all 6 authors...
CT and MR imaging play an important role in the evaluation of retroperitoneal masses, especially in characterization and the assessment of the extent of the disease and involvement of adjacent and distant structures.
#1Shiji SuzukiH-Index: 1
#2Satoshi KajiH-Index: 3
Last. Shinichi BanH-Index: 21
view all 8 authors...
Context We report the imaging features of pancreatic schwannomas, a rare benign type of pancreatic tumor. Case report A 66-year-old woman was admitted to our hospital with a pancreatic tumor indicated in medical examinations. Computed tomography (CT), magnetic resonance imaging (MRI) and endoscopic ultrasonography (EUS) revealed a solid and cystic tumor, 3 cm in diameter, within the body of the pancreas. Contrast-enhanced CT, MRI and ultrasonography showed partial enhancement in the solid compon...
#1Aditya Gupta (Providence Hospital)H-Index: 7
#2Gokulakkrishna Subhas (Providence Hospital)H-Index: 13
Last. Michael J. Jacobs (Providence Hospital)H-Index: 15
view all 4 authors...
Pancreatic schwannoma is a rare neoplasm. Accurate preoperative diagnosis remains difficult, but computed tomography (CT) scanning and magnetic resonance imaging (MRI) help to establish the diagnosis, and definitive diagnosis requires immunohistochemical examination. Cystic pancreatic schwannomas should be considered in the differential diagnosis of cystic neoplasms and pseudocysts. Simple enucleation may be adequate for pancreatic schwannoma. In this report, we examine a case of benign pancreat...
#1Franz J. Wippold (WashU: Washington University in St. Louis)H-Index: 33
#2M. LubnerH-Index: 1
Last. Arie PerryH-Index: 109
view all 5 authors...
SUMMARY: Histologic patterns of cellular architecture often suggest a tissue diagnosis. Distinctive histologic patterns seen within the peripheral nerve sheath tumor schwannoma include the Antoni A and Antoni B regions. The purpose of this report is to review the significance of Antoni regions in the context of schwannomas.
Cited By0
This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.