Lithium preserves peritoneal membrane integrity by suppressing mesothelial cell αB-crystallin
Abstract
Life-saving renal replacement therapy by peritoneal dialysis (PD) is limited in use and duration by progressive impairment of peritoneal membrane integrity and homeostasis. Preservation of peritoneal membrane integrity during chronic PD remains an urgent but long unmet medical need. PD therapy failure results from peritoneal fibrosis and angiogenesis caused by hypertonic PD fluid (PDF)-induced mesothelial cytotoxicity. However, the...
Paper Details
Title
Lithium preserves peritoneal membrane integrity by suppressing mesothelial cell αB-crystallin
Published Date
Aug 25, 2021
Volume
13
Issue
608
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