Novel model combining contrast-enhanced ultrasound with serology predicts hepatocellular carcinoma recurrence after hepatectomy

Published on Aug 26, 2021in World Journal of Clinical Cases1.013
· DOI :10.12998/WJCC.V9.I24.7009
Haibin Tu , Lihong Chen9
Estimated H-index: 9
+ 3 AuthorsYong-Yi Zeng
Novel model combining contrast-enhanced ultrasound with serology predicts hepatocellular carcinoma recurrence after hepatectomy
#1Ikuo Nakamura (Hyogo College of Medicine)H-Index: 4
#2Etsuro Hatano (Hyogo College of Medicine)H-Index: 55
Last. Hiroko Iijima (Hyogo College of Medicine)H-Index: 28
view all 13 authors...
This study aimed to clarify what hepatocellular carcinoma (HCC) phenotype, as categorized by intraoperative contrast-enhanced ultrasonography (CEUS), showed a high risk of recurrence after hepatic resection. Patients who underwent initial curative hepatectomy with intraoperative CEUS for a single HCC nodule were retrospectively assigned to three patterns of fine (FI), vascular (VA), and irregular (IR) according to the maximum intensity projection pattern based on intraoperative CEUS. Staining wa...
2 CitationsSource
#1Hyuna Sung (ACS: American Cancer Society)H-Index: 19
#2Jacques Ferlay (IARC: International Agency for Research on Cancer)H-Index: 77
Last. Freddie Bray (IARC: International Agency for Research on Cancer)H-Index: 119
view all 7 authors...
This article provides an update on the global cancer burden using the GLOBOCAN 2020 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer. Worldwide, an estimated 19.3 million new cancer cases (18.1 million excluding nonmelanoma skin cancer) and almost 10.0 million cancer deaths (9.9 million excluding nonmelanoma skin cancer) occurred in 2020. Female breast cancer has surpassed lung cancer as the most commonly diagnosed cancer, with an estimated ...
2,490 CitationsSource
#1Feng Zhang (Fudan University)H-Index: 155
#2Shenxin Lu (Fudan University)H-Index: 1
Last. Xin Yin (Fudan University)H-Index: 15
view all 11 authors...
Objective Albumin-to-alkaline phosphatase ratio (AAPR), a newly developed blood biomarker, has been reported to have prognostic value in several types of cancer. This study aimed to investigate the predictive value of AAPR in patients with early-stage hepatocellular carcinoma (HCC) undergoing radiofrequency ablation (RFA) as initial therapy. Methods This retrospective study analyzed 445 patients with newly diagnosed HCC undergoing RFA as initial therapy. A series of survival analyses were perfor...
3 CitationsSource
#1Jing Lv (Fudan University)H-Index: 4
#2Hongyan Yin (Fudan University)H-Index: 3
Last. Hongcheng Shi (Fudan University)H-Index: 16
view all 4 authors...
PURPOSE The aim of this study is to investigate the value of pre-treatment 18F-FDG PET/CT in predicting the pathological characteristic of HCC and recurrence after liver transplantation (LT). METHODS A total of 34 patients who underwent 18F-FDG PET/CT before LT for HCC and did not receive any other treatment were retrospectively enrolled in the study. The maximal standard uptake value of the tumor (T-SUVmax), normal liver tissues (L-SUVmax), and mediastinal blood pool (B-SUVmax) were derived, fo...
1 CitationsSource
Last. Zhang Guoqiang (ZJU: Zhejiang University)
view all 6 authors...
ABSTRACT To investigate whether MRI features could preoperatively predict local tumor progression (LTP) in patients with hepatocellular carcinoma (HCC) treated with radiofrequency ablation (RFA) as the first-line treatment and improve a novel predictive model through developing a nomogram including various conventional MRI parameters. 105 patients with HCCs who had received RFA were enrolled. All patients had undergone conventional MRI before RFA. Uni- and multivariable analyses for LTP were ass...
1 CitationsSource
#1Christine KochH-Index: 9
#2Theresa BetteH-Index: 1
Last. Martin-Walter WelkerH-Index: 12
view all 13 authors...
Background/aims Hepatocellular carcinoma (HCC) is a leading indication for liver transplantation (LT) worldwide. Early identification of patients at risk for HCC recurrence is of paramount importance since early treatment of recurrent HCC after LT may be associated with increased survival. We evaluated incidence of and predictors for HCC recurrence, with a focus on the course of AFP levels. Methods We performed a retrospective, single-center study of 99 HCC patients who underwent LT between Janu...
2 CitationsSource
#1Meghan BellH-Index: 3
#2Evrim B. Turkbey (NIH: National Institutes of Health)H-Index: 27
Last. Freddy E. EscorciaH-Index: 11
view all 3 authors...
Ultrasound, computed tomography, magnetic resonance imaging, and [F]F-fluorodeoxyglucose positron emission tomography are invaluable in the clinical evaluation of human cancers. Radiomics and radiogenomics tools may allow clinicians to standardize interpretation of these conventional imaging modalities, while better linking radiographic hallmarks to disease biology and prognosis. These advances, coupled with next-generation positron emission tomography imaging tracers capable of providing biolog...
4 CitationsSource
#1Guwei JiH-Index: 7
#2Fei-Peng Zhu (Peking Union Medical College)H-Index: 2
Last. Xue-Hao WangH-Index: 6
view all 8 authors...
Proposed radiomics models integrating pre- and postoperative variables helped predict tumor recurrence before and after resection for early stage hepatocellular carcinoma.
32 CitationsSource
#1Kei Morio (Hiroshima University)H-Index: 15
#2Tomokazu Kawaoka (Hiroshima University)H-Index: 28
Last. Kazuaki ChayamaH-Index: 124
view all 20 authors...
Abstract Purpose In recent years, it has been reported that use of 18F-FDG PET-CT can reveal the degree of hepatocellular carcinoma malignancy. We evaluate the ability of a preoperative 18F-FDG PET-CT to predict the recurrence of extrahepatic metastasis of HCC after surgery. Methods We retrospectively examined 67 patients who received 18F-FDG PET-CT prior to curative hepatic resection for HCC between April 2010 and March 2016. Multivariate Cox regression analysis was performed to identify the fa...
2 CitationsSource
#1Peigang Ning (Zhengzhou University)H-Index: 5
#2Fei GaoH-Index: 3
Last. Dapeng Shi (Zhengzhou University)H-Index: 19
view all 8 authors...
Purpose To appraise the ability of the computed tomography (CT) radiomics signature for prediction of early recurrence (ER) in patients with hepatocellular carcinoma (HCC).
10 CitationsSource
Cited By0