hsa‑miR‑15b‑5p regulates the proliferation and apoptosis of human vascular smooth muscle cells by targeting the ACSS2/PTGS2 axis

A previous bioinformatic analysis from our group predicted that the interaction of microRNA (miRNA/miR)‑15b with the acyl‑CoA synthetase short chain family member 2 (ACSS2) gene was important for the development of abdominal aortic aneurysm (AAA). Apoptosis of aortic vascular smooth muscle cells (VSMCs) is a pathological feature of AAA. The present study aimed to explain the roles of miR‑15b/ACSS2 in AAA by exploring their effects on the...