Annual Tuberculosis Preventive Therapy for Persons With HIV Infection

Tuberculosis preventive therapy for persons with HIV infection is effective, but its durability is uncertain.To compare treatment completion rates of weekly isoniazid-rifapentine for 3 months versus daily isoniazid for 6 months as well as the effectiveness of the 3-month rifapentine-isoniazid regimen given annually for 2 years versus once.Randomized trial. (ClinicalTrials.gov: NCT02980016).South Africa, Ethiopia, and Mozambique.Persons with HIV...