Effects of Advanced Glycation End Products on Differentiation and Function of Osteoblasts and Osteoclasts
Abstract
Risk of fragility fractures increases in patients with diabetes mellitus, independent of bone mineral density. In the present study, the effects of advanced glycation end products (AGEs) on differentiation and function of osteoblasts and osteoclasts were investigated.AGEs and 25 mM glucose were administered to marrow-derived macrophages and MCT3T3-E1 cells. The effects of AGEs on osteoclast differentiation was investigated using...
Paper Details
Title
Effects of Advanced Glycation End Products on Differentiation and Function of Osteoblasts and Osteoclasts
Published Date
Jan 1, 2021
Volume
36
Issue
37
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