Chronic Kidney Disease Associated with Worsening White Matter Disease and Ventricular Enlargement

Chronic kidney disease (CKD), a growing public health issue in the elderly, is associated with increased risk of cognitive impairment.To investigate the mechanisms through which CKD impacts brain health using longitudinal imaging.We identified 97 participants (74 CKD and 23 non-CKD) from the BRINK (BRain IN Kidney Disease), a longitudinal study of CKD with two MRI scans (baseline and 3-year follow-up). We measured the associations between...