Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
Abstract
Behaviors and disorders related to self-regulation, such as substance use, antisocial behavior and attention-deficit/hyperactivity disorder, are collectively referred to as externalizing and have shared genetic liability. We applied a multivariate approach that leverages genetic correlations among externalizing traits for genome-wide association analyses. By pooling data from ~1.5 million people, our approach is statistically more powerful than...
Paper Details
Title
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
Published Date
Aug 26, 2021
Journal
Volume
24
Issue
10
Pages
1367 - 1376
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