C3 and C4 complement levels in AQP4-IgG-positive NMOSD and in MOGAD
Abstract
While complement-dependent cytotoxicity (CDC) is a known effector mechanism in aquaporin-4-immunoglobulin (Ig)G-positive (AQP4-IgG+) neuromyelitis optica spectrum disorder (NMOSD), the role of CDC in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is less clear. We determined complement C3 and C4 plasma concentrations in patients with clinically stable AQP4-IgG+ NMOSD (n = 16), MOGAD (n = 15), early multiple sclerosis...
Paper Details
Title
C3 and C4 complement levels in AQP4-IgG-positive NMOSD and in MOGAD
Published Date
Nov 1, 2021
Journal
Volume
360
Pages
577699 - 577699
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