Fixed Drug Eruption Induced by Pristinamycin and Amoxicillin–Clavulanic Acid: An Unusual Case of Cosensitization

To the Editor: Fixed drug eruption (FDE) is a cutaneous reaction triggered by several drugs.1 Although cross-reactivity between drugs with structural similarity has been reported, cosensitization between chemically unrelated agents was rarely described.2 We report the first case of FDE caused by pristinamycin and amoxicillin–clavulanic acid (AMC), confirmed by oral provocation tests (OPTs). A 75-year-old man, with a history of diabetes and...