Selenium-GPX4 axis protects follicular helper T cells from ferroptosis.

Volume: 22, Issue: 9, Pages: 1127 - 1139
Published: Aug 19, 2021
Abstract
Follicular helper T (TFH) cells are a specialized subset of CD4+ T cells that essentially support germinal center responses where high-affinity and long-lived humoral immunity is generated. The regulation of TFH cell survival remains unclear. Here we report that TFH cells show intensified lipid peroxidation and altered mitochondrial morphology, resembling the features of ferroptosis, a form of programmed cell death that is driven by...
Paper Details
Title
Selenium-GPX4 axis protects follicular helper T cells from ferroptosis.
Published Date
Aug 19, 2021
Volume
22
Issue
9
Pages
1127 - 1139
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.