Working HAND in HAND: Central Nervous System Complications in People with Human Immunodeficiency Virus

To the Editor—Looking back, in 2005 leading investigators met in Frascati, Italy, to help devise new research criteria for defining human immunodeficiency virus (HIV)–associated neurocognitive disorders (HANDs). These criteria were not published until 2007 [1]. Revised nomenclature was established to define milder impairment: asymptomatic neurocognitive impairment and mild neurocognitive disorder. Both conditions were defined by impaired...