Laminin Polymerization and Inherited Disease: Lessons From Genetics
Abstract
The laminins (LM) are a family of basement membranes glycoproteins with essential structural roles in supporting epithelia, endothelia, nerves and muscle adhesion, and signaling roles in regulating cell migration, proliferation, stem cell maintenance and differentiation. Laminins are obligate heterotrimers comprised of α, β and γ chains that assemble intracellularly. However, extracellularly these heterotrimers then assemble into higher-order...
Paper Details
Title
Laminin Polymerization and Inherited Disease: Lessons From Genetics
Published Date
Aug 12, 2021
Journal
Volume
12
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