Impaired function of epithelial plakophilin‐2 is associated with periodontal disease

Volume: 56, Issue: 6, Pages: 1046 - 1057
Published: Aug 9, 2021
Abstract
Plakophilin-2 (PKP2) is an intracellular desmosomal anchoring protein that has been implicated in a genome-wide association study, in which genetic variants of PKP2 are associated with Porphyromonas gingivalis (P.gingivalis) -dominant periodontal dysbiosis. In this study, we compared the ex vivo PKP2 expression in periodontitis gingival biopsies to periodontitis-free subjects and assessed the in vitro role of PKP2 in gingival epithelial barrier...
Paper Details
Title
Impaired function of epithelial plakophilin‐2 is associated with periodontal disease
Published Date
Aug 9, 2021
Volume
56
Issue
6
Pages
1046 - 1057
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