L‐malic acid production from xylose by engineered Saccharomyces cerevisiae
Abstract
L-malic acid is widely used in the food, chemical, and pharmaceutical industries. Here, we report on production of malic acid from xylose, the second most abundant sugar in lignocellulosic hydrolysates, by engineered Saccharomyces cerevisiae. To enable malic acid production in a xylose-assimilating S. cerevisiae, we overexpressed PYC1 and PYC2, coding for pyruvate carboxylases, a truncated MDH3 coding for malate dehydrogenase, and SpMAE1, coding...
Paper Details
Title
L‐malic acid production from xylose by engineered Saccharomyces cerevisiae
Published Date
Aug 25, 2021
Journal
Volume
17
Issue
3
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