Effect of the hydrogenation solvent in the PHIP-SAH hyperpolarization of [1- 13 C]pyruvate
Abstract
ParaHydrogen Induced Polarization-Side Arm Hydrogenation (PHIP-SAH) is an inexpensive tool to obtain hyperpolarized pyruvate (and other metabolites) that can be applied to in-vivo diagnostics, for the investigation of metabolic processes. This method is based on hydrogenation, using hydrogen enriched in the para-isomer, of unsaturated substrates, catalyzed, usually, by a homogeneous rhodium(I) complex. In this work, the effect of the solvent on...
Paper Details
Title
Effect of the hydrogenation solvent in the PHIP-SAH hyperpolarization of [1- 13 C]pyruvate
Published Date
Aug 3, 2021
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