Matrix stiffness controls ciliogenesis and centriole position

Published: Aug 12, 2021
Abstract
Mechanical stress and the stiffness of the extracellular matrix are key drivers of tissue development and homeostasis. Aberrant mechanosensation is associated with a wide range of pathologies, including diseases such as osteoarthritis. Substrate stiffness is one of the well-known mechanical properties of the matrix that enabled establishing the central dogma of an integrin-mediated mechanotransduction using stem cells. However, how specific...
Paper Details
Title
Matrix stiffness controls ciliogenesis and centriole position
Published Date
Aug 12, 2021
Journal
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