Dendritic cells maintain anti-tumor immunity by positioning CD8 skin-resident memory T cells

Volume: 4, Issue: 10, Pages: e202101056 - e202101056
Published: Aug 6, 2021
Abstract
Tissue-resident memory (TRM) T cells are emerging as critical components of the immune response to cancer; yet, requirements for their ongoing function and maintenance remain unclear. APCs promote TRM cell differentiation and re-activation but have not been implicated in sustaining TRM cell responses. Here, we identified a novel role for dendritic cells in supporting TRM to melanoma. We showed that CD8 TRM cells remain in close proximity to...
Paper Details
Title
Dendritic cells maintain anti-tumor immunity by positioning CD8 skin-resident memory T cells
Published Date
Aug 6, 2021
Volume
4
Issue
10
Pages
e202101056 - e202101056
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