Rechallenge of immune checkpoint inhibitors: A systematic review and meta-analysis

• Rechallenge ICI is an active and feasible strategy. • Rechallenge ICI could be considered on an individual basis. • Prospective studies are needed to clarify the role of rechallenge ICI. The role of immune checkpoint inhibitors (ICI) rechallenge in cancer patients is not defined. When ICIs are discontinued due to treatment completion or toxicity, another course of ICIs is feasible in clinical practice, but the amount of data is still quite...