Efficacy and safety of sotagliflozin in patients with type 2 diabetes and severe renal impairment
Abstract
To assess the efficacy and safety of sotagliflozin, a dual inhibitor of sodium-glucose cotransporter-1 and -2, in adults with type 2 diabetes (T2D) and stage 4 chronic kidney disease (CKD4).This 52-week, phase 3, randomized (1:1:1), placebo-controlled trial evaluated sotagliflozin 200 mg and sotagliflozin 400 mg once daily in 277 patients with T2D and estimated glomerular filtration rate (eGFR) 15 to 30 mL/min/1.73 m2 . The primary endpoint was...
Paper Details
Title
Efficacy and safety of sotagliflozin in patients with type 2 diabetes and severe renal impairment
Published Date
Aug 20, 2021
Volume
23
Issue
12
Pages
2632 - 2642
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