Contrasting genomic profiles from metastatic sites, primary tumors, and liquid biopsies of advanced prostate cancer

Cancer6.20
Volume: 127, Issue: 24, Pages: 4557 - 4564
Published: Aug 11, 2021
Abstract
This study assessed the contrasting genomic profiles from the primary tumors (PTs), metastatic (MET) sites, and circulating tumor DNA (ctDNA) of patients with prostate cancer (PC).A total of 1294 PC tissue specimens and 2462 ctDNA specimens underwent hybrid capture-based comprehensive genomic profiling (CGP). Specimens included tissue from PTs; MET biopsies from bone, liver (LIV), lung (LU), brain (BN), lymph node, and soft tissue sites; and...
Paper Details
Title
Contrasting genomic profiles from metastatic sites, primary tumors, and liquid biopsies of advanced prostate cancer
Published Date
Aug 11, 2021
Journal
Volume
127
Issue
24
Pages
4557 - 4564
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