Use of mixture design to optimize nanofabrication of dithiocarbazate–loaded polylactic acid nanoparticles

In recent years, polyester polymers such as poly(lactic acid) (PLA) have been extensively studied for drug delivery systems due to their biocompatible, biodegradable, and nontoxic pharmacological properties. Moreover, dithiocarbazate Schiff bases containing sulfur‐nitrogen donor atoms are interesting in the context of coordination chemistry and pharmacological applications. The aim of the present study was to optimize the encapsulation of...