Development of poly(Ɛ-polycaprolactone)/hydroxyapatite composites for bone tissue regeneration

The incorporation of osteoconductive hydroxyapatite (HA) into poly(Ɛ-polycaprolactone) (PCL) may enhance the material hydrophilicity, protein adsorption, roughness, and consequently, bone formation. In this work, PCL/HA composites with 5, 10, and 25 wt% of HA were prepared by melt compounding followed by hot compression, and their properties such as torque, molecular weight, mechanical resistance, and viscosity were compared to neat PCL to...