Endoscopic ultrasound-guided fine-needle biopsy: size really does matter!

Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) has become the gold standard for the diagnosis of pancreatic and peripancreatic masses, often achieving a sensitivity of 90 %, with a specificity of 100 % [1]. It is not clear whether the size of needle used matters, with a recent meta-analysis demonstrating similar sensitivity, specificity, and safety profiles for 22 G and 25 G FNA needles [2]. However, FNA needles are limited by: a...