Preclinical data suggest role of dopamine in preventing select skin cancers

Animal studies and laboratory data show a central role for dopamine in preventing squamous cell carcinoma of the skin through its activation of receptors involved in inhibiting the development and progression of premalignant lesions. Little is known about dopamine's role in premalignant tumors. In malignant tumors, dopamine is thought to regulate vascular endothelial growth factor A (VEGF)–induced angiogenesis. To examine whether dopamine may...