Atypic SUMOylation of Nor1/NR4A3 regulates neural cell viability and redox sensitivity

Neuron‐derived orphan receptor 1, NR4A3 (Nor1)/NR4A3 is an orphan nuclear receptor involved in the transcriptional control of developmental and neurological functions. Oxidative stress‐induced conditions are primarily associated with neurological defects in humans, yet the impact on Nor1‐mediated transcription of neuronal genes remains with unknown mechanism. Here, we demonstrate that Nor1 is a non‐conventional target of SUMO2/3 conjugation at...