The cyto-protective effects of LH on ovarian reserve and female fertility during exposure to gonadotoxic alkylating agents in an adult mouse model

Does LH protect mouse oocytes and female fertility from alkylating chemotherapy?LH treatment before and during chemotherapy prevents detrimental effects on follicles and reproductive lifespan.Chemotherapies can damage the ovary, resulting in premature ovarian failure and reduced fertility in cancer survivors. LH was recently suggested to protect prepubertal mouse follicles from chemotoxic effects of cisplatin treatment.This experimental study...