Effect of Polyphosphorylation on Behavior of Protein Disordered Regions

Volume: 22, Issue: 15, Pages: 7883 - 7883
Published: Jul 23, 2021
Abstract
Proteins interact with many charged biological macromolecules (polyelectrolytes), including inorganic polyphosphates. Recently a new protein post-translational modification, polyphosphorylation, or a covalent binding of polyphosphate chain to lysine, was demonstrated in human and yeast. Herein, we performed the first molecular modeling study of a possible effect of polyphosphorylation on behavior of the modified protein using replica exchange...
Paper Details
Title
Effect of Polyphosphorylation on Behavior of Protein Disordered Regions
Published Date
Jul 23, 2021
Volume
22
Issue
15
Pages
7883 - 7883
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