Effects of Stephania hainanensis alkaloids on MSU-induced acute gouty arthritis in mice

Background Gout is initiated by the precipitation of monosodium urate (MSU) crystals within the joints and soft tissues, and it can eventually cause acute or chronic arthritis. MSU crystals trigger, amplify, and maintain a strong inflammatory response through promoting proinflammatory activity. In this study, the therapeutic effects of Stephania hainanensis ( S. hainanensis ) total alkaloid (SHA) were tested and evaluated on MSU-induced acute...