Peptide-Based Inhibitors of ADAM and ADAMTS Metalloproteinases

Volume: 8
Published: Jul 21, 2021
Abstract
ADAM and ADAMTS are two large metalloproteinase families involved in numerous physiological processes, such as shedding of cell-surface protein ectodomains and extra-cellular matrix remodelling. Aberrant expression or dysregulation of ADAMs and ADAMTSs activity has been linked to several pathologies including cancer, inflammatory, neurodegenerative and cardiovascular diseases. Inhibition of ADAM and ADAMTS metalloproteinases have been attempted...
Paper Details
Title
Peptide-Based Inhibitors of ADAM and ADAMTS Metalloproteinases
Published Date
Jul 21, 2021
Volume
8
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