COVID-19 Deliveries: Maternal Features and Neonatal Outcomes

Published on Jul 19, 2021in Journal of Patient-Centered Research and Reviews
路 DOI :10.17294/2330-0698.1848
Viviana Zlochiver1
Estimated H-index: 1
,
Blair L. Tilkens1
Estimated H-index: 1
+ 2 AuthorsM. Fuad Jan14
Estimated H-index: 14
(UW: University of Wisconsin-Madison)
Sources
Abstract
Integrated, data-driven criteria are necessary to evaluate delivery outcomes in pregnancies affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the ongoing COVID-19 pandemic. This study analyzed maternal demographics, clinical characteristics, treatments, and delivery outcomes of 85 ethnically diverse, adult pregnant women who tested positive for SARS-CoV-2 at the time of delivery. Median maternal and gestational ages were 27 years (interquartile range [IQR]: 23-31) and 39 weeks (IQR: 37.3-40.0), respectively. Of the 85 SARS-CoV-2-positive participants, 67 (79%) had no COVID-19 symptoms at the time of routine COVID-19 admission testing, 14 (16%) reported mild COVID-19 symptoms, and 4 (5%) presented severe COVID-19 symptoms that required hospitalization. Patients in the severe COVID-19 group had significantly longer hospitalizations than those with nonsevere COVID-19 (7 [IQR: 4.5-9.5] vs 2 [IQR: 2-3] days; P<0.01). Neonatal outcomes included 100% live births with a median 1-minute Apgar score of 8 and 15% preterm births. No neonatal deaths or vertical transmissions were reported, and all neonatal intensive care unit admissions were related to prematurity. Overall, maternal symptom prevalence and peripartum complication rates were low, suggesting a generally good prognosis for pregnant women with SARS-CoV-2 infections at the time of delivery.
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#1Steven ChenH-Index: 1
#2Peter S. BernsteinH-Index: 27
Last. Shamantha ReddyH-Index: 2
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Introduction The Bronx is a borough of New York City that has been profoundly affected by the COVID-19 pandemic. Limited reports exist discussing the anaesthetic management of obstetric patients infected with COVID-19. We review a cohort of obstetric patients in the Bronx with COVID-19 and report their delivery data, anaesthetic management, and maternal-fetal outcomes. Material and methods We reviewed 92 pregnant patients with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 ...
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#5Camille A. Clare (SUNY: State University of New York System)H-Index: 8
While data have shown that Black populations are disproportionately affected by COVID-19, few studies have evaluated birth outcomes in these understudied populations. This study hypothesized that SARS-CoV-2 infection would confer worse maternal and neonatal outcomes in a predominantly Black and underserved population in Brooklyn, New York City. In particular, SARS-CoV-2 is associated with higher rates of preterm birth, cesarean delivery, postpartum hemorrhage, lower APGAR scores, and neonatal re...
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#1K GhemaH-Index: 1
#2M. Lehlimi (Boston Children's Hospital)H-Index: 2
Last. S. Benomar (Boston Children's Hospital)H-Index: 3
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Abstract Introduction Coronavirus disease 2019 (COVID-19) has spread rapidly across the world. Given the sharply increased infection rate, the number of pregnant women and children with COVID-19 is correspondingly on the rise. SARS-CoV-2 infection is transmitted through droplets; though hypothesized, other transmission routes have not been confirmed. As of now, it remains unclear whether and how SARS-CoV-2 can possibly be transmitted from the mother to the fetus. Method This study examines the m...
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#1Irina Oltean (Children's Hospital of Eastern Ontario)H-Index: 1
#2Jason Tran (U of O: University of Ottawa)H-Index: 1
Last. Dina El Demellawy (U of O: University of Ottawa)H-Index: 14
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Abstract Pregnant women are susceptible to viral infections due to physiological changes such as cell-mediated immunity. No severe adverse pregnancy or neonatal outcomes have been consistently reported in 2019 novel coronavirus disease (COVID-19) positive pregnancy cases. There are controversies around the role of COVID-19 in pregnancy. A systematic review was conducted to examine clinical maternal and neonatal clinical outcomes. Studies were included if they reported SARS-CoV-2 infection among ...
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#1Peilin Zhang (Houston Methodist Hospital)H-Index: 13
#2Taryn Heyman (Houston Methodist Hospital)H-Index: 4
Last. Sanford Lederman (Houston Methodist Hospital)H-Index: 4
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COVID19 is caused by a newly identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) that affects pregnant women equally to the general population. How SARS-CoV2 affects the mothers,...
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#1Kavita Narang (Mayo Clinic)H-Index: 5
#2Elizabeth Ann L. Enninga (Mayo Clinic)H-Index: 13
Last. Vesna D. Garovic (Mayo Clinic)H-Index: 54
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Abstract The global pandemic of SARS-CoV-2, the cause of Coronavirus disease 2019 (COVID-19), has been associated with worse outcomes in several patient populations, including the elderly and those with chronic comorbidities. Data from previous pandemics and seasonal influenza suggest that pregnant women may be at increased risk for infection-associated morbidity and mortality. Physiological changes in normal pregnancy and metabolic and vascular changes of high-risk pregnancies may affect pathog...
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OBJECTIVE: To characterize symptoms and disease severity among pregnant women with coronavirus disease 2019 (COVID-19) infection, along with laboratory findings, imaging, and clinical outcomes. METHODS: Pregnant women with COVID-19 infection were identified at two affiliated hospitals in New York City from March 13 to April 19, 2020, for this case series study. Women were diagnosed with COVID-19 infection based on either universal testing on admission or testing because of COVID-19-related sympt...
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#2Erkan Kalafat (METU: Middle East Technical University)H-Index: 15
Last. Laura A. Magee ('KCL': King's College London)H-Index: 71
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#1Seo Hee Yoon (Boston Children's Hospital)H-Index: 7
#2J-M KangH-Index: 1
Last. Jong Gyun AhnH-Index: 10
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OBJECTIVE: To evaluate the clinical manifestations and outcomes of neonates born to women who had Coronavirus Disease 2019 (COVID-19) during pregnancy. MATERIALS AND METHODS: A systematic literature search was conducted on PubMed and Embase till April 15, 2020, by combining the terms (COVID-19, Severe Acute Respiratory Syndrome Coronavirus 2, SARS-CoV-2, Novel Coronavirus, 2019-nCov, Wuhan pneumonia) and (pregnancy, pregnant women, mother, fetus, neonate, newborn, infant). RESULTS: We included 1...
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#1Farida Elshafeey (Ain Shams University)H-Index: 2
#2Rana Magdi (Ain Shams University)H-Index: 2
Last. Ashraf Nabhan (Ain Shams University)H-Index: 18
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BACKGROUND: Clinical presentation and outcomes of COVID-19 infection during pregnancy remain limited and fragmented. OBJECTIVES: To summarize the existing literature on COVID-19 infection during pregnancy and childbirth, particularly concerning clinical presentation and outcomes. SEARCH STRATEGY: A systematic search of LitCovid, EBSCO MEDLINE, CENTRAL, CINAHL, Web of Science, and Scopus electronic databases. The references of relevant studies were also searched. SELECTION CRITERIA: Identified ti...
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