Architecture of cell–cell junctions in situ reveals a mechanism for bacterial biofilm inhibition
Volume: 118, Issue: 31
Published: Jul 28, 2021
Abstract
Many bacteria, including the major human pathogen Pseudomonas aeruginosa, are naturally found in multicellular, antibiotic-tolerant biofilm communities, in which cells are embedded in an extracellular matrix of polymeric molecules. Cell-cell interactions within P. aeruginosa biofilms are mediated by CdrA, a large, membrane-associated adhesin present in the extracellular matrix of biofilms, regulated by the cytoplasmic concentration of cyclic...
Paper Details
Title
Architecture of cell–cell junctions in situ reveals a mechanism for bacterial biofilm inhibition
Published Date
Jul 28, 2021
Volume
118
Issue
31
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