Multiscale mechanical responses of young and elderly human femurs: A finite element investigation

Bone remodeling in the elderly is no longer balanced. As a result, the morphologies and mechanical properties of bone at different scales will change. These changes would affect the mechanical responses of bone, which might exacerbate the imbalance of bone remodeling and even cause age-related bone diseases.Considering those changes, multiscale finite element (FE) models of bone in the young and the elderly were developed that included...