Mutations in two SARS-CoV-2 variants of concern reflect two distinct strategies of antibody escape
Abstract
Understanding the factors that contribute to antibody escape of SARS-CoV-2 and its variants is key for the development of drugs and vaccines that provide broad protection against a variety of virus variants. Using microfluidic diffusional sizing, we determined the dissociation constant ( K D ) for the interaction between receptor binding domains (RBDs) of SARS-CoV-2 in its original version (WT) as well as alpha and beta variants with the...
Paper Details
Title
Mutations in two SARS-CoV-2 variants of concern reflect two distinct strategies of antibody escape
Published Date
Jul 26, 2021
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