Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study

Circulating vitamin C concentrations have been associated with several cancers in observational studies, but little is known about the causal direction of the associations. This study aims to explore the potential causal relationship between circulating vitamin C and risk of five most common cancers in Europe.We used summary-level data for genetic variants associated with plasma vitamin C in a large vitamin C genome-wide association study (GWAS)...