Gα15 in early onset of pancreatic ductal adenocarcinoma
Abstract
The GNA15 gene is ectopically expressed in human pancreatic ductal adenocarcinoma cancer cells. The encoded Gα15 protein can promiscuously redirect GPCR signaling toward pathways with oncogenic potential. We sought to describe the distribution of GNA15 in adenocarcinoma from human pancreatic specimens and to analyze the mechanism driving abnormal expression and the consequences on signaling and clinical follow-up. We detected GNA15 expression in...
Paper Details
Title
Gα15 in early onset of pancreatic ductal adenocarcinoma
Published Date
Jul 21, 2021
Journal
Volume
11
Issue
1
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