Refined prognostic staging for resected pancreatic cancer by modified stage grouping and addition of tumour grade

With changes in T and N categories the 8th edition of the AJCC/UICC TNM staging system for pancreatic cancer resulted in improved prognostic staging, but inconsistencies were observed with specific stage groups. Tumour grading remains disregarded in prognostic staging. We aimed to validate the current staging system and to investigate the possibility of further optimization by integration of grading.1946 patients undergoing upfront surgical...