Defining super-enhancer landscape in triple-negative breast cancer by multiomic profiling
Abstract
Breast cancer is a heterogeneous disease, affecting over 3.5 million women worldwide, yet the functional role of cis-regulatory elements including super-enhancers in different breast cancer subtypes remains poorly characterized. Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with a poor prognosis. Here we apply integrated epigenomic and transcriptomic profiling to uncover super-enhancer heterogeneity between...
Paper Details
Title
Defining super-enhancer landscape in triple-negative breast cancer by multiomic profiling
Published Date
Apr 14, 2021
Journal
Volume
12
Issue
1
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