Physciosporin suppresses mitochondrial respiration, aerobic glycolysis, and tumorigenesis in breast cancer
Abstract
Physciosporin (PHY) is one of the potent anticancer lichen compound. Recently, PHY was shown to suppress colorectal cancer cell proliferation, motility, and tumorigenesis through novel mechanisms of action. We investigated the effects of PHY on energy metabolism and tumorigenicity of the human breast cancer (BC) cells MCF-7 (estrogen and progesterone positive BC) and MDA-MB-231 (triple negative BC). The anticancer effect of PHY on cell...
Paper Details
Title
Physciosporin suppresses mitochondrial respiration, aerobic glycolysis, and tumorigenesis in breast cancer
Published Date
Oct 1, 2021
Journal
Volume
91
Pages
153674 - 153674
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