Water content changes in new multiple sclerosis lesions have a minimal effect on the determination of myelin water fraction values
Abstract
Myelin water fraction (MWF) is a histopathologically validated in vivo myelin marker. As MWF is the proportion of water with a short T2 relative to the total water, increases in water from edema and inflammation may confound MWF determination in multiple sclerosis (MS) lesions. Total water content (TWC) measurement enables calculation of absolute myelin water content (MWC) and can be used to distinguish edema/inflammation from demyelination. We...
Paper Details
Title
Water content changes in new multiple sclerosis lesions have a minimal effect on the determination of myelin water fraction values
Published Date
Jul 26, 2021
Journal
Volume
31
Issue
6
Pages
1119 - 1125
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