The peroxisomal transporter ABCD3 plays a major role in dicarboxylic fatty acid metabolism

Published: Jul 26, 2021
Abstract
null Peroxisomes metabolize a specific subset of fatty acids, which include dicarboxylic fatty acids (DCAs) generated by ω-oxidation. Data obtained in vitro suggest that the peroxisomal transporter ABCD3 (also known as PMP70) mediates the transport of DCAs into the peroxisome, but in vivo evidence to support this role is lacking. In this study, we studied an Abcd3 KO mouse model generated by CRISPR-Cas9 technology using targeted and untargeted...
Paper Details
Title
The peroxisomal transporter ABCD3 plays a major role in dicarboxylic fatty acid metabolism
Published Date
Jul 26, 2021
Journal
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