Uncovering the pathophysiology of irritable bowel syndrome by exploring the gut-brain axis: a narrative review

Objective: To improve the pathophysiological understanding of irritable bowel syndrome (IBS) by exploring the gut-brain axis.Background: Disorders of gut-brain interaction (DGBIs) are gastrointestinal (GI) disorders in which alterations in bowel functions occur. IBS, which is one of the most studied DGBIs, is linked with abdominal distress or pain without obvious structural or biochemical anomalies.Methods: The etiology of IBS has not been...