Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women

Volume: 12, Issue: 1
Published: Jul 7, 2021
Abstract
Our study describes breast cancer risk loci using a cross-ancestry GWAS approach. We first identify variants that are associated with breast cancer at P < 0.05 from African ancestry GWAS meta-analysis (9241 cases and 10193 controls), then meta-analyze with European ancestry GWAS data (122977 cases and 105974 controls) from the Breast Cancer Association Consortium. The approach identifies four loci for overall breast cancer risk [1p13.3, 5q31.1,...
Paper Details
Title
Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women
Published Date
Jul 7, 2021
Volume
12
Issue
1
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